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Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas A Randomized Controlled Trial (Green Journal of OB/GYN)

Every year we are required as part of our board certification to read a large number of scientific articles with questions.  This article is on our list for 2019.  Now Both relugolix and AbbVie's elagolix are oral drugs that do the same thing as Lupron, an injectable drug that has been around since the late 1980's.  I have

Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas A Randomized Controlled Trial (Green Journal of OB/GYN)2020-02-04T20:03:27+00:00

Research Indicates Male’s Frequent Marijuana Use Tied To Elevated Miscarriage Risk in Female Partners

Marijuana may be becoming legal but it is still a drug that will have significant negative effects in humans with its use. Michael D. Fox, MD Jacksonville Center Reproductive Medicine https://www.medscape.com/viewarticle/921799

Research Indicates Male’s Frequent Marijuana Use Tied To Elevated Miscarriage Risk in Female Partners2020-01-16T15:20:46+00:00

Chlamydia Increases Risk For Pelvic Inflammatory Disease, Ectopic Pregnancy, Female Infertility, Study Suggests

I think it is not widely known in the public arena that Chlamydia infection, even treated timely, can result in tubal infertility.  We see everything from normal fertility outcome to requiring IVF to achieve pregnancy.  Even when the tubes look perfectly normal at surgery this may  be the case.  Prevention of STD's is still the

Chlamydia Increases Risk For Pelvic Inflammatory Disease, Ectopic Pregnancy, Female Infertility, Study Suggests2020-01-15T16:45:02+00:00

Research Indicates The Rate Of High Blood Pressure During Pregnancy Increased Over Last 40 Years

Research Indicates The Rate Of High Blood Pressure During Pregnancy Increased Over Last 40 Years In the age-period-cohort analysis, the rate of chronic hypertension increased sharply with advancing age and period from 0.11% in 1970 to 1.52% in 2010 (rate ratio, 13.41; 95% CI, 13.22–13.61).  While the absolute numbers are not that large, this represents

Research Indicates The Rate Of High Blood Pressure During Pregnancy Increased Over Last 40 Years2020-01-15T17:02:36+00:00

Only 13 Percent Of Women Have 28-Day Menstrual Cycles, Study Suggests

The interpretation of this data points to variation in cycles from month to month stating that fertility may vary from "cycle to cycle."  My take on this would be to realize that our women today are subjected to enormous physiologic stress which is causing the changes in the cycle length.  27-29 days are normal and

Only 13 Percent Of Women Have 28-Day Menstrual Cycles, Study Suggests2020-02-04T20:03:50+00:00

Marijuana Use In Pregnancy Persists Despite Dangers, Research Shows

More trouble on the Marijuana front.  Just as I predicted more and more women will see the "legalization" of marijuana as a pronouncement of safety for use even in pregnancy.  We are seeing a dramatic increase in patients who report marijuana use in the infertility population.  As more people begin to "consume" this drug, it

Marijuana Use In Pregnancy Persists Despite Dangers, Research Shows2020-01-16T04:14:44+00:00

Researchers Examine Relationship Between Work Hours And Risk Of Miscarriage Or Preterm Birth

Here is more support for sleep disruption as a dramatic stressor in reproduction.  We have noticed that physiologic stress patients that we term "hypothalamic dysfunction" seem to have a much greater chance of miscarriage as well as no pregnancy or infertility.  This study makes the basic connection and is in no way proof of causation

Researchers Examine Relationship Between Work Hours And Risk Of Miscarriage Or Preterm Birth2020-01-16T05:14:25+00:00

Study Shows Women With Endometriosis More Likely To Use Opioids For Prolonged Periods, Use Benzodiazepines Concomitantly

Of course this is the case.  The medical system is failing endometriosis patients in a dramatic way.  If you were taught that endometriosis surgery doesn't work and that it recurs anyway, and that most medicines to treat pain only work or are allowed to be used short term, then as a doctor you really don't

Study Shows Women With Endometriosis More Likely To Use Opioids For Prolonged Periods, Use Benzodiazepines Concomitantly2020-01-16T05:18:20+00:00

Research Indicates Children Conceived Through ART Do Not Face Increased Cancer Risk

Research Indicates Children Conceived Through ART Do Not Face Increased Cancer Risk These studies from small countries like the Netherlands are helpful because their socialized systems do allow for accurate data collection and likely capture most events in the healthcare system for the country.  This safe bill of health from a cancer standpoint is reassuring

Research Indicates Children Conceived Through ART Do Not Face Increased Cancer Risk2020-01-16T18:33:01+00:00

Fertility Clinics Reportedly Refusing Treatment To Women With High BMI

  https://www.nytimes.com/2019/06/18/magazine/fertility-weight-obesity-ivf.html This is certainly a very emotional and controversial subject.  To read the coverage on this, you would think doctors are refusing care to patients because they don't like people who are overweight.  This is far from the truth.  A host of studies that look at IVF outcome based on BMI (body mass index

Fertility Clinics Reportedly Refusing Treatment To Women With High BMI2020-01-16T18:36:04+00:00