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Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas A Randomized Controlled Trial (Green Journal of OB/GYN)

Every year we are required as part of our board certification to read a large number of scientific articles with questions.  This article is on our list for 2019.  Now Both relugolix and AbbVie's elagolix are oral drugs that do the same thing as Lupron, an injectable drug that has been around since the late 1980's.  I have

Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas A Randomized Controlled Trial (Green Journal of OB/GYN)2020-02-04T20:03:27+00:00

Pre-Eclampsia May Increase Mother’s Risk For Future Cardiovascular Disease And Earlier Death, Research Indicates

If one reads this medical headline from ACOG to our nations physicians, one would assume/conclude that pre-eclampsia (high blood pressure in pregnancy) itself is responsible for the increase in cardiovascular disease.  This is a classic example so common in medical "reporting" in the media.  The following is the article title. Title:  Preeclampsia and Cardiovascular Disease in

Pre-Eclampsia May Increase Mother’s Risk For Future Cardiovascular Disease And Earlier Death, Research Indicates2020-02-04T20:03:32+00:00

Chlamydia Increases Risk For Pelvic Inflammatory Disease, Ectopic Pregnancy, Female Infertility, Study Suggests

I think it is not widely known in the public arena that Chlamydia infection, even treated timely, can result in tubal infertility.  We see everything from normal fertility outcome to requiring IVF to achieve pregnancy.  Even when the tubes look perfectly normal at surgery this may  be the case.  Prevention of STD's is still the

Chlamydia Increases Risk For Pelvic Inflammatory Disease, Ectopic Pregnancy, Female Infertility, Study Suggests2020-01-15T16:45:02+00:00

Research Indicates The Rate Of High Blood Pressure During Pregnancy Increased Over Last 40 Years

Research Indicates The Rate Of High Blood Pressure During Pregnancy Increased Over Last 40 Years In the age-period-cohort analysis, the rate of chronic hypertension increased sharply with advancing age and period from 0.11% in 1970 to 1.52% in 2010 (rate ratio, 13.41; 95% CI, 13.22–13.61).  While the absolute numbers are not that large, this represents

Research Indicates The Rate Of High Blood Pressure During Pregnancy Increased Over Last 40 Years2020-01-15T17:02:36+00:00

Research Suggests Increase In Obesity-Related Cancers In Middle Age

An increase in cancer is obvious to those of us caring for patients.  From the time I was a child and in high school (1970's) until now there has been a dramatic increase in cancer.  This is true of statistics and just my general impression.  I don't remember knowing of any cancer in any of

Research Suggests Increase In Obesity-Related Cancers In Middle Age2020-01-16T05:12:13+00:00

Researchers Examine Relationship Between Work Hours And Risk Of Miscarriage Or Preterm Birth

Here is more support for sleep disruption as a dramatic stressor in reproduction.  We have noticed that physiologic stress patients that we term "hypothalamic dysfunction" seem to have a much greater chance of miscarriage as well as no pregnancy or infertility.  This study makes the basic connection and is in no way proof of causation

Researchers Examine Relationship Between Work Hours And Risk Of Miscarriage Or Preterm Birth2020-01-16T05:14:25+00:00

Estradiol May Have Protective Effect Against Cognitive Impairment In Women With Visceral Adipose Tissue, Research Suggests

More evidence that estrogen is protective to brain function and hopefully inching the needle toward more acceptance of normalization of estrogen for women.  The headwinds and resistance still abound when it comes to estrogen use in women. Newer studies are showing that if estrogen is started early, when the decline starts that cognitive function may

Estradiol May Have Protective Effect Against Cognitive Impairment In Women With Visceral Adipose Tissue, Research Suggests2020-01-16T05:16:20+00:00

Study Shows Women With Endometriosis More Likely To Use Opioids For Prolonged Periods, Use Benzodiazepines Concomitantly

Of course this is the case.  The medical system is failing endometriosis patients in a dramatic way.  If you were taught that endometriosis surgery doesn't work and that it recurs anyway, and that most medicines to treat pain only work or are allowed to be used short term, then as a doctor you really don't

Study Shows Women With Endometriosis More Likely To Use Opioids For Prolonged Periods, Use Benzodiazepines Concomitantly2020-01-16T05:18:20+00:00

Research Suggests Possible Link Between Processed Food Consumption In Pregnancy And Increased Risk Of Autism In Offspring

I know everyone gets tired of me blaming all health evils on carbohydrates, but it is the largest ingested toxin in our world by a magnitude of 100X to the next largest offender.  In roughly 2008 or so a good friend of mine, a pediatrician, a great one by the way who will remain nameless

Research Suggests Possible Link Between Processed Food Consumption In Pregnancy And Increased Risk Of Autism In Offspring2020-01-16T05:20:12+00:00

Fertility Clinics Reportedly Refusing Treatment To Women With High BMI

  https://www.nytimes.com/2019/06/18/magazine/fertility-weight-obesity-ivf.html This is certainly a very emotional and controversial subject.  To read the coverage on this, you would think doctors are refusing care to patients because they don't like people who are overweight.  This is far from the truth.  A host of studies that look at IVF outcome based on BMI (body mass index

Fertility Clinics Reportedly Refusing Treatment To Women With High BMI2020-01-16T18:36:04+00:00